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Associate Scientist / Scientist – Cell Line Development

Job Description

Main Responsibilities

In this role you will primarily be responsible for CHO cell line generation and process development.

Some additional key responsibilities include:

  • Plasmid DNA preparation
  • CHO cell line development for expression of monoclonal antibodies, bispecific antibodies, Fc-fusions and other therapeutic proteins
  • CHO cell culture process development
  • Protein/Antibody biochemical interaction analysis using ForteBio Octet, ELISA, and/or FACS

 

Additional Skills/Preferences

  • Consistent track record and strong working knowledge of CHO cell culture
  • Exceptionally strong communication and problem-solving skills
  • Strong working knowledge/understanding of stable CHO expression
  • Media & feed development experience
  • Process development experience
  • Bioreactor expression experience
  • Equipment handling experience such as ClonePix, CSI et al
  • Pharmaceutical and/or biotech experience particularly relevant to this position

Qualifications:
Master in Immunology/Cell Biology/Chemical Engineering/Biochemical Engineering or related subject with 1-3 years of experience, or Bachelor with more than 3 years of experience.

Benefits

AskGene Pharma Inc. offers competitive salary and benefits. Main benefits include 401K match, performance-based bonus, medical insurance, and paid vacation per year.

Job Type: Full-time

Interested applicants should click on the link to fill out the contact form.  Please attach a cover letter and resume.

Associate Scientist – Upstream Process Development

Job Description

Main Responsibilities

  • Reporting to the director of the upstream process Development team, you will be responsible for the cell line/upstream process development to support process development and manufacturing activities (e.g. stable cell line generation and characterization and various bioreactors operation). You will also involve in tech transfer, process scale up and CMO management.
  • This is an entry level hands-on scientist position. You will design and carry out experiments, perform general laboratory activities that include the routine maintenance of equipment and will keep an accurate laboratory record (lab notebook) of all experiments. You will also write technical reports when needed.

Basic requirements

  • Master in Chemical Engineering/Biochemical Engineering/Cell Biology or related subject with 1-3 years of postdoctoral experience.
  • Experience of working in a laboratory focused on protein expression is desirable.
  • Knowledge of DoE and statistics software such as JMP, Minitab or design expert is desirable.
  • Knowledge of using process stimulation software such as CFD is a big plus.
  • Hard working, organized, and work well in team setting.
  • Provide solutions to a variety of problems of diverse scope involving basic scientific principles.
  • Desire to learn and build on the role.

Preferred requirements

  • Previous experience with large scale protein production from mammalian and/or microbial systems.
  • Bioreactor/fermenter operation experience.

Benefits

AskGene Pharma Inc. offers competitive salary and benefits. Main benefits include 401K match, performance-based bonus, medical insurance, and three weeks of paid vacation per year.

Job Type: Full-time

Interested applicants should click on the link to fill out the contact form.  Please attach a cover letter and resume.

Research Associate/Scientist – Analytical Science

Job Description

Main Responsibilities

  • Reporting to Director of Analytical Science, you will be responsible for the development of protein analytical methods to support process and product development.  You will be performing the analysis using standard methods that include HPLC, CE, SDS-PAGE, Western Blot, and/or ELISA.
  • In this hands-on role, you will be part of a team support protein and antibody drug discovery and development.  You will perform general laboratory activities that include the routine maintenance of equipment and will maintain a current and accurate laboratory record (lab notebook) of all activities. Your duties will also include report writing/presentations to team, department, company and externally.

Essential requirements

  • Master of Science degree with 3 or more years of working experience.
  • Experience of working in a laboratory focused on analysis of proteins and antibodies.
  • Protein chemistry experience.
  • Hard working, organized, and work well in team setting.
  • Provide solutions to a variety of problems of diverse scope involving basic scientific principles.
  • Desire to learn and build on the role.
  • Must be legally authorized to work in the US without sponsorship

Desirable requirements

  • Previous experience with analysis and characterization of proteins and/or antibodies desirable.
  • Experience with HPLC, CE, SDS-PAGE, Western and ELISA.
  • Experience with LCMS is a plus.

Benefits

AskGene Pharma Inc. offers competitive salary and benefits. Main benefits include 401K match, performance-based bonus, medical insurance, and three weeks of paid vacation per year.

Job Type: Full-time

Interested applicants should click on the link to fill out the contact form.  Please attach a cover letter and resume.